A corneal abrasion is a scratch or scrape on the surface of your cornea. Corneal abrasions are often caused by fingernails, cosmetic brushes, and tree branches. Other causes of corneal abrasion include rubbing your eyes and having particularly dry eyes.
The cornea is densely packed with nerve cells. Pain receptor cells transmit pain to alert us to possible injury to the eye's surface. Our cornea has hundreds of times more pain receptors than our skin. |
EXOSOME THERAPY-CELLTIXCelltiX represents a distinct extracellular vesicle derived from Umbilical Cord-Derived Mesenchymal Stem Cells (MSCs), produced in a cGMP-compliant facility. This innovative variation of a significant paracrine factor, discharged by MSCs into a culture medium, assumes a crucial role across a diverse array of biological processes.
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STEM CELL THERAPY-CELLTIMAXCelltiMax is a product sourced from human umbilical cord-derived Mesenchymal Stem Cells (MSCs). These cells undergo a cultivation process before being introduced to the patient through intramuscular or intravenous injections.
Notably, these cells exhibit low immunogenicity, ensuring safety, high tolerance, and a lack of side effects. Furthermore, they possess the remarkable capability to transform into specialized cells, each tailored to perform distinct functions in various bodily regions. Additionally, these cells contribute to alleviating inflammation, facilitating repair, rejuvenation, regeneration, and the replacement of impaired cells. |
CELLULAR THERAPY-SCITRONScitron represents Mesenchymal Stem Cells (MSCs) sourced from human umbilical cords. Following cultivation, these cells are introduced into the patient's body via intramuscular or intravenous injections. A distinctive attribute of these cells is their minimal immunogenicity, which ensures a high level of safety, tolerance, and the absence of adverse effects.
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CRITERIAS |
STEM CELL |
EXOSOMES |
Definition |
Stem cells are unspecialized cells of the human body |
Extracellular vesicles, which is the medical term for tiny bubbles that are released from stem cells |
Function |
Unique, can become any type of cell, and they act as both building blocks and repair mechanisms in your body |
Carry genetic information and proteins to cells throughout your body, and they create paths for communication between cells |
Origins |
Donor stem cells are placed in your body and are guided into becoming specific cells in the body to replace and repair diseased cells |
Exosomes are extracted from donated human mesenchymal stem cells (MSCs) and sterilized |
Growth Factors |
Less amount of growth factors compared to exosomes |
Exosomes contain nearly three times the amount of growth factors. More growth factors mean a better ability to restore and revitalize target cells |
Administration |
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STEM CELL THERAPY |
EXOSOME THERAPY |
CELLULAR THERAPY |
Improve bodies' natural healing abilities |
High stabililty |
Improve bodies' natural healing abilities |
Modulate the immune system |
Low toxicity and immunogenicity |
Modulate the immune system |
Locate and reduce areas of inflammation |
High penetration |
Locate and reduce areas of inflammation |
Replace damaged and diseased cells |
Enhanced delivery efficiency |
Replace damaged and diseased cells |
Subconjunctival injection of mesenchymal stem cells for corneal failure due to limbal stem cell deficiency.
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Differentiation of Mesenchymal Stem Cells (MSCs) and paracrine signaling via exosomes are widely employed to mediate these effects. The cell-free nature of exosomes allows them to circumvent challenges related to cell-fate control and tumorigenesis. Additionally, the vesicle content can be genetically modified to optimize therapeutic affinity. Current research primarily focuses on pharmacology, toxicology, xeno-free processing with sustained delivery, scaling up production in accordance with Good Manufacturing Practice (GMP) regulations, and cost-effectiveness. Furthermore, investigations encompass injection, topical application, and/or utilization of engineered bioscaffolds as potential administration routes for treating corneal diseases. |
CELL TISSUE TECHNOLOGY SDN BHD
Malaysia's FIRST Tissue Engineering Firm |
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