Corneal Abrasion

INTRODUCTION

Corneal Abrasion: A scratch or scrape on the surface of your cornea. Corneal abrasions are often caused by fingernails, cosmetic brushes, or tree branches.

CORNEAL ABRASION

A corneal abrasion is a scratch or scrape on the surface of your cornea. Corneal abrasions are often caused by fingernails, cosmetic brushes, and tree branches. Other causes of corneal abrasion include rubbing your eyes and having particularly dry eyes.

The cornea is densely packed with nerve cells. Pain receptor cells transmit pain to alert us to possible injury to the eye's surface. Our cornea has hundreds of times more pain receptors than our skin.

SYMPTOMS

If you've scratched your eye before, you’ll probably remember how it feels. If not, you might:

Feel like you have sand or grit in your eye.
Experience pain, especially when you open or close your eye.
Notice tearing and redness.
Become sensitive to light.
Have blurred vision

WHAT CAUSES THE DISEASE?

You might get a scratch if you:

Poke your eye with a fingernail, pen, or makeup brush.
Get dirt, sand, sawdust, ash, or some other foreign matter in your eye.
Get chemicals in your eye.
Rub it too hard.
Wear poor-fitting or dirty contact lenses.
Get a certain type of eye infection.
Have surgery without proper eye protection.
Play sports or engage in high-risk physical activity without safe eyewear.
Overwear your contact lenses.

You may not feel symptoms right away. As a result, you may not be able to determine the cause immediately.

CURRENT TREATMENTS

To prevent worsening of the condition, refrain from rubbing your eyes if you have a corneal abrasion. It is advisable to seek guidance from an eye doctor for the most appropriate approach to treating a corneal abrasion. Your doctor will conduct an examination of the eye and remove any foreign objects if present. Anesthetic eye drops can be used to make this procedure more comfortable.

Minor corneal abrasions typically heal within a few days. Your doctor might recommend eye drops to maintain eye moisture and reduce the risk of infection. Following the prescribed instructions for using these eye drops is crucial. Additionally, discontinuing the use of contact lenses for a period may be necessary. Larger corneal abrasions take longer to heal compared to smaller ones.

Patients experiencing severe pain or sensitivity to light may receive oral pain medication until the abrasion heals. It's important to note that topical numbing agents (anesthetics) used in the doctor's office for examination and treatment should never be self-administered at home due to potential adverse effects from repeated use.

WHAT WE OFFER?

EXOSOME THERAPY-CELLTIX

CelltiX represents a distinct extracellular vesicle derived from Umbilical Cord-Derived Mesenchymal Stem Cells (MSCs), produced in a cGMP-compliant facility. This innovative variation of a significant paracrine factor, discharged by MSCs into a culture medium, assumes a crucial role across a diverse array of biological processes.

STEM CELL THERAPY-CELLTIMAX

CelltiMax is a product sourced from human umbilical cord-derived Mesenchymal Stem Cells (MSCs). These cells undergo a cultivation process before being introduced to the patient through intramuscular or intravenous injections.

Notably, these cells exhibit low immunogenicity, ensuring safety, high tolerance, and a lack of side effects. Furthermore, they possess the remarkable capability to transform into specialized cells, each tailored to perform distinct functions in various bodily regions. Additionally, these cells contribute to alleviating inflammation, facilitating repair, rejuvenation, regeneration, and the replacement of impaired cells.

CELLULAR THERAPY-SCITRON

Scitron represents Mesenchymal Stem Cells (MSCs) sourced from human umbilical cords. Following cultivation, these cells are introduced into the patient's body via intramuscular or intravenous injections. A distinctive attribute of these cells is their minimal immunogenicity, which ensures a high level of safety, tolerance, and the absence of adverse effects.

COMPARISON BETWEEN STEM CELLS AND EXOSOMES

CRITERIAS	STEM CELL	EXOSOMES
Definition	Stem cells are unspecialized cells of the human body	Extracellular vesicles, which is the medical term for tiny bubbles that are released from stem cells
Function	Unique, can become any type of cell, and they act as both building blocks and repair mechanisms in your body	Carry genetic information and proteins to cells throughout your body, and they create paths for communication between cells
Origins	Donor stem cells are placed in your body and are guided into becoming specific cells in the body to replace and repair diseased cells	Exosomes are extracted from donated human mesenchymal stem cells (MSCs) and sterilized
Growth Factors	Less amount of growth factors compared to exosomes	Exosomes contain nearly three times the amount of growth factors. More growth factors mean a better ability to restore and revitalize target cells
Administration	IV Stem Cell Therapy (Intravenous administration) Intrathecal (directly into the spinal canal) Site injections into problem areas (Knee, hips, hands, etc)	Intravenous (IV) therapy Direct injection in the treatment area

BENEFITS OF OUR TREATMENTS

STEM CELL THERAPY	EXOSOME THERAPY	CELLULAR THERAPY
Improve bodies' natural healing abilities	High stabililty	Improve bodies' natural healing abilities
Modulate the immune system	Low toxicity and immunogenicity	Modulate the immune system
Locate and reduce areas of inflammation	High penetration	Locate and reduce areas of inflammation
Replace damaged and diseased cells	Enhanced delivery efficiency	Replace damaged and diseased cells

HOW IT WORKS?

Subconjunctival injection of mesenchymal stem cells for corneal failure due to limbal stem cell deficiency.

Differentiation of Mesenchymal Stem Cells (MSCs) and paracrine signaling via exosomes are widely employed to mediate these effects. The cell-free nature of exosomes allows them to circumvent challenges related to cell-fate control and tumorigenesis. Additionally, the vesicle content can be genetically modified to optimize therapeutic affinity. Current research primarily focuses on pharmacology, toxicology, xeno-free processing with sustained delivery, scaling up production in accordance with Good Manufacturing Practice (GMP) regulations, and cost-effectiveness. Furthermore, investigations encompass injection, topical application, and/or utilization of engineered bioscaffolds as potential administration routes for treating corneal diseases.

TALK TO US

If you believe that our treatment options may be able to improve your condition and enhance your quality of life, please contact us to schedule a complimentary consultation with one of our in-house clinical specialists. Our consultations are available in both Malay and English language.