A corneal abrasion is a scratch or scrapes on your cornea's surface. Corneal abrasions are frequently caused by fingernails, cosmetics brushes, and tree branches.Other causes of corneal abrasion include rubbing your eyes and having particularly dry eyes.
The cornea is densely packed with nerve cells. Pain receptor cells transmit pain to alert us to possible injury to the eye's surface. Our cornea has hundreds of times more pain receptors than our skin. |
EXOSOME THERAPY-CELLTIXCelltiX is a type of extracellular vesicle from Umbilical Cord-Derived Mesenchymal Stem Cells (MSCs) manufactured in a cGMP-compliant facility. It is a novel form of a major paracrine factor released by MSCs into a culture medium, which plays an important role in a wide range of biological processes.
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STEM CELL THERAPY-CELLTIMAXCelltiMax is a product derived from human umbilical cord-derived Mesenchymal Stem Cells (MSCs). The cells are cultured, then administered to the patient via intramuscular or intravenous injection.
The cells have low immunogenicity making them safe, well-tolerated and free of side effects. They have the ability to differentiate into specialized cells with specific functions for various parts of the body, and can reduce inflammation, repair, renew, regenerate, and replace damaged cells. |
CELLULAR THERAPY-SCITRONScitron is a Mesenchymal Stem Cells (MSCs), derived from human umbilical cords. Upon treatment, the cultured cells are injected intramuscularly or intravenously into the patient. The cells are characterized by low immunogenicity, making them very safe, tolerable, and free of side effects.
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CRITERIAS |
STEM CELL |
EXOSOMES |
Definition |
Stem cells are unspecialized cells of the human body |
Extracellular vesicles, which is the medical term for tiny bubbles that are released from stem cells |
Function |
Unique, can become any type of cell, and they act as both building blocks and repair mechanisms in your body |
Carry genetic information and proteins to cells throughout your body, and they create paths for communication between cells |
Origins |
Donor stem cells are placed in your body and are guided into becoming specific cells in the body to replace and repair diseased cells |
Exosomes are extracted from donated human mesenchymal stem cells (MSCs) and sterilized |
Growth Factors |
Less amount of growth factors compared to exosomes |
Exosomes contain nearly three times the amount of growth factors. More growth factors mean a better ability to restore and revitalize target cells |
Administration |
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STEM CELL THERAPY |
EXOSOME THERAPY |
CELLULAR THERAPY |
Improve bodies' natural healing abilities |
High stabililty |
Improve bodies' natural healing abilities |
Modulate the immune system |
Low toxicity and immunogenicity |
Modulate the immune system |
Locate and reduce areas of inflammation |
High penetration |
Locate and reduce areas of inflammation |
Replace damaged and diseased cells |
Enhanced delivery efficiency |
Replace damaged and diseased cells |
Subconjunctival injection of mesenchymal stem cells for corneal failure due to limbal stem cell deficiency.
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MSC differentiation and paracrine signaling via exosomes are widely used to mediate these effects. Exosomes' cell-free nature allows them to avoid problems with cell-fate control and tumorigenesis, and the vesicle content can be genetically modified for optimal therapeutic affinity. The current research focus is on pharmacology and toxicology, xeno-free processing with sustained delivery, scale-up production in compliance with Good Manufacturing Practice regulations, and cost-effectiveness. Injection, topical, and/or engineered bioscaffold administration routes are also being investigated for their potential use in treating corneal diseases. |
CELL TISSUE TECHNOLOGY SDN BHD
Malaysia's FIRST Tissue Engineering Firm |
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