Corneal Abrasion

INTRODUCTION

Corneal abrasion : a scratch or scrapes on your cornea's surface. Corneal abrasions are frequently caused by fingernails, cosmetics brushes, and tree branches.

CORNEAL ABRASION

A corneal abrasion is a scratch or scrapes on your cornea's surface. Corneal abrasions are frequently caused by fingernails, cosmetics brushes, and tree branches.Other causes of corneal abrasion include rubbing your eyes and having particularly dry eyes.

The cornea is densely packed with nerve cells. Pain receptor cells transmit pain to alert us to possible injury to the eye's surface. Our cornea has hundreds of times more pain receptors than our skin.

SYMPTOMS

If you've scratched your eye before, you’ll probably remember how it feels. If not, you might:

Feel like you have sand or grit in your eye
Have pain, especially when you open or close your eye
Notice tearing and redness
Become sensitive to light
Have blurred vision

WHAT CAUSES THE DISEASE?

You might get a scratch if you:

Poke your eye with a fingernail, pen, or makeup brush
Get dirt, sand, sawdust, ash, or some other foreign matter in your eye
Get chemicals in your eye
Rub it too hard
Wear poor-fitting or dirty contact lenses
Get a certain type of eye infection
Have surgery without proper eye protection
Play sports or engage in high-risk physical activity without safe eyewear
Overwear your contact lenses

You may not feel symptoms right away. As a result, you may not be able to figure out what caused it.

CURRENT TREATMENTS

You should avoid rubbing your eyes if you have a corneal abrasion. Only an eye doctor can advise you on the best way to treat a corneal abrasion. Your doctor will inspect the eye and remove any unwanted items discovered. This treatment will be made more comfortable by using anesthetic eye drops.

Minor corneal abrasions usually heal within a few days. Eye drops may be recommended by the doctor to keep the eye moist and to lessen the risk of infection. It is critical to use these eye drops exactly as directed. It may also be required to discontinue the use of contact lenses for a period. Larger corneal abrasions heal more slowly than smaller ones.

Patients with severe pain or light sensitivity may be prescribed oral pain medication until the abrasion recovers. Because of the harmful effects of repeated administration of these medications, topical numbing agents (anesthetics) that may be used in the office to allow examination and treatment should never be used at home.

WHAT WE OFFER?

EXOSOME THERAPY-CELLTIX

CelltiX is a type of extracellular vesicle from Umbilical Cord-Derived Mesenchymal Stem Cells (MSCs) manufactured in a cGMP-compliant facility. It is a novel form of a major paracrine factor released by MSCs into a culture medium, which plays an important role in a wide range of biological processes.

STEM CELL THERAPY-CELLTIMAX

CelltiMax is a product derived from human umbilical cord-derived Mesenchymal Stem Cells (MSCs). The cells are cultured, then administered to the patient via intramuscular or intravenous injection.

The cells have low immunogenicity making them safe, well-tolerated and free of side effects. They have the ability to differentiate into specialized cells with specific functions for various parts of the body, and can reduce inflammation, repair, renew, regenerate, and replace damaged cells.

CELLULAR THERAPY-SCITRON

Scitron is a Mesenchymal Stem Cells (MSCs), derived from human umbilical cords. Upon treatment, the cultured cells are injected intramuscularly or intravenously into the patient. The cells are characterized by low immunogenicity, making them very safe, tolerable, and free of side effects.

COMPARISON BETWEEN STEM CELLS AND EXOSOMES

CRITERIAS	STEM CELL	EXOSOMES
Definition	Stem cells are unspecialized cells of the human body	Extracellular vesicles, which is the medical term for tiny bubbles that are released from stem cells
Function	Unique, can become any type of cell, and they act as both building blocks and repair mechanisms in your body	Carry genetic information and proteins to cells throughout your body, and they create paths for communication between cells
Origins	Donor stem cells are placed in your body and are guided into becoming specific cells in the body to replace and repair diseased cells	Exosomes are extracted from donated human mesenchymal stem cells (MSCs) and sterilized
Growth Factors	Less amount of growth factors compared to exosomes	Exosomes contain nearly three times the amount of growth factors. More growth factors mean a better ability to restore and revitalize target cells
Administration	IV Stem Cell Therapy (Intravenous administration) Intrathecal (directly into the spinal canal) Site injections into problem areas (Knee, hips, hands, etc)	Intravenous (IV) therapy Direct injection in the treatment area

BENEFITS OF OUR TREATMENTS

STEM CELL THERAPY	EXOSOME THERAPY	CELLULAR THERAPY
Improve bodies' natural healing abilities	High stabililty	Improve bodies' natural healing abilities
Modulate the immune system	Low toxicity and immunogenicity	Modulate the immune system
Locate and reduce areas of inflammation	High penetration	Locate and reduce areas of inflammation
Replace damaged and diseased cells	Enhanced delivery efficiency	Replace damaged and diseased cells

HOW IT WORKS?

Subconjunctival injection of mesenchymal stem cells for corneal failure due to limbal stem cell deficiency.

MSC differentiation and paracrine signaling via exosomes are widely used to mediate these effects. Exosomes' cell-free nature allows them to avoid problems with cell-fate control and tumorigenesis, and the vesicle content can be genetically modified for optimal therapeutic affinity. The current research focus is on pharmacology and toxicology, xeno-free processing with sustained delivery, scale-up production in compliance with Good Manufacturing Practice regulations, and cost-effectiveness. Injection, topical, and/or engineered bioscaffold administration routes are also being investigated for their potential use in treating corneal diseases.

TALK TO US

If you believe that our treatment options may be able to improve your condition and enhance your quality of life, please contact us to schedule a complimentary consultation with one of our in-house clinical specialists. Our consultations are available in both Malay and English language.