INTRODUCTION
Chronic renal disease, usually referred to as CKD or chronic kidney disease, is a disorder in which kidney function gradually declines over time while acute kidney disease which is referred as AKD is a rapid decrease in renal function over days to weeks.
The illustration of healthy and unhealthy kidney
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ACUTE/CHRONIC KIDNEY DISEASEAcute/chronic kidney disease (A/CKD), commonly known as kidney failure or renal failure, is a medical disorder where the kidneys lose some of their capacity to filter waste materials and extra fluid from the bloodstream. The accumulation of waste materials and fluids in the body can have a negative impact on other body systems and our health.
The reason the condition is referred to as "chronic" is because the kidneys' damage develops gradually over a lengthy period of time. Besides, acute kidney disease refers to a sudden episode of kidney failure or kidney damage that happens within a few hours or a few days. |
STAGES OF KIDNEY DISEASES
Stages of kidney disease
SYMPTOMS
People with A/CKD may not feel ill or notice any symptoms. The only way to find out is through specific blood and urine tests. These tests include the measurement of both the creatinine level in the blood and protein in the urine.
As kidney disease gets worse, a person may have swelling, called edema. Edema happens when the kidneys can’t get rid of extra fluid and salt. Edema can occur in the legs, feet, or ankles, and less often in the hands or face.
Other symptoms of advanced A/CKD are chest pain, itching or numbness, muscle cramps, nausea, weight loss, sleep problems, shortness of breath, headaches, increased or decreased urination, and blood in the urine.
As kidney disease gets worse, a person may have swelling, called edema. Edema happens when the kidneys can’t get rid of extra fluid and salt. Edema can occur in the legs, feet, or ankles, and less often in the hands or face.
Other symptoms of advanced A/CKD are chest pain, itching or numbness, muscle cramps, nausea, weight loss, sleep problems, shortness of breath, headaches, increased or decreased urination, and blood in the urine.
WHAT CAUSES THE DISEASE?
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Diabetes, hypertension, cardiovascular diseases (CVD), and cigarette smoking are the common risk factors of chronic kidney disease (CKD).
The common causes of acute kidney failure include:
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Causes of chronic kidney disease
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CURRENT TREATMENT
The treatment of acute/chronic kidney disease will depend on the stage of the kidney disease. There are several main treatments which are
1. Medicine
There's no medicine specifically for acute/chronic kidney disease, but medicine can help control many of the problems that cause the condition and the complications that can happen as a result of it.
CAUSES |
NAME OF MEDICINE |
High blood pressure |
Angiotensin Converting Enzyme (ACE) |
High cholesterol |
Statins |
High potassium |
Sodium Zirconium Cyclosilicate |
Anaemia |
Iron |
Bone problems |
Calcium acetate Calcium carbonate |
2. Dialysis
This is a method of removing waste products and excess fluid from the blood. However, dialysis is not regarded as the best course of treatment due to the high expenses of care and detrimental effects on the patient's quality of life
An alternative to dialysis for people with severely reduced kidney function is a kidney transplant. This is often the most effective treatment for advanced kidney disease, but it involves major surgery and taking medicines (immunosuppressants) to stop the body attacking the donor organ. Besides, its usage is restricted because to the severe lack of organ donors and the possibility of organ rejection.
This is a method of removing waste products and excess fluid from the blood. However, dialysis is not regarded as the best course of treatment due to the high expenses of care and detrimental effects on the patient's quality of life
- Haemodialysis – this involves diverting blood into an external machine, where it's filtered before being returned to the body
- Peritoneal dialysis – this involves pumping dialysis fluid into a space inside your tummy to draw out waste products from the blood as they pass through vessels lining the inside of your tummy
An alternative to dialysis for people with severely reduced kidney function is a kidney transplant. This is often the most effective treatment for advanced kidney disease, but it involves major surgery and taking medicines (immunosuppressants) to stop the body attacking the donor organ. Besides, its usage is restricted because to the severe lack of organ donors and the possibility of organ rejection.
EXOSOME THERAPY
CELLTIXCelltiX is an extracted vesicle derived from mesenchymal stem cells (MSCs) obtained from umbilical cords. Our state-of-the-art cGMP facility is responsible for the preparation of CelltiX. This innovative product represents a new category of major paracrine factors released by MSCs into a culture medium, playing a pivotal role in a wide array of biological processes.
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STEM CELL THERAPY
CELLTIMAXCelltiMax comprises Mesenchymal Stem Cells (MSCs) derived from human umbilical cords. After treatment, the cultured cells are intramuscularly or intravenously injected into the patient. These cells possess low immunogenicity, ensuring safety, tolerability, and minimal side effects. They have the ability to differentiate into specialized cells with distinct functions across various body parts. Their capacities encompass reducing inflammation, repairing, renewing, regenerating, and replacing damaged cells.
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BENEFITS OF OUR TREATMENT
STEM CELL THERAPY |
EXOSOME THERAPY |
Accelerates healing |
Reduced inflammation |
Eliminates pain and inflammation |
Supports metabolic function |
Avoids the need for surgery |
Improve brain health |
Enhances collagen production |
Reduces chronic pain |
Decrease nerve damage |
Enhances tissue regeneration |
Less invasive procedure |
Boost immune health |
HOW IT WORKS?
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Acute kidney disease
Chronic kidney disease
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Mechanism of Mesenchymal stem cells to kidney
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TALK TO US
If you feel we might be able to offer meaningful improvement to both your condition and your quality of life, then please reach out to schedule a free consultation with one of our in-house clinical experts. We offer consultations in both Malay and English.
During your consultation, we will:
Review your medical history & recent evaluations
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Explore what your treatment package might look like
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Answer any questions you have about us
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Answer any questions you have about the therapies
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Discuss practical next steps,
if you feel we can effectively treat you |
To schedule your consultation, click the button below
CELL TISSUE TECHNOLOGY SDN BHD
Malaysia's FIRST Tissue Engineering Firm |
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